The following 13 researchers are working at the Hakubi Center for Advanced Research, Kyoto University.
:Global Type
:Tenure-track Type
Research Interests: Protein Design and Engineering
Research Topic: Protein Design and Engineering Toward the Creation of Bionanorobot
Host Department: Graduate School of Human and Environmental Studies
Previous Affiliation: Graduate School of Medicine, Kyoto University
The ability of chemists to act as "designers" to modify protein structure and functions using a combination of rationale design and directed evolution has the potential to usher in the new era allowing the development of “smart bionanorobots programmed to perform multiple tasks for biotechnology applications”. Such "protein nanorobots" could play active roles in the field of medicine and biotechnology, and development of this technology may not be far away. However, existing protein designs require advanced techniques in order to control the diversity and complexity of protein structures. Therefore, the probability of such success is still low, and many trials-and-errors are required. So far, only primitive construction of protein assembly has been achieved. For this reason, I propose to conduct research to establish “new protein design and engineering methodology” that maximizes the actual and natural characteristics of protein targets toward creating “smart bionanorobots”, rather than forcefully controlling such potentials and characteristics.
Research activity status (external page)