The Hakubi Project

1st

Short Introduction

Hirohide was born and raised in Osaka. After completing predoctoral training at SUNY Buffalo in USA, he received his Ph.D. from the University of Tokyo in 2002. He is interested in the field of RNA synthetic biology and the origin of life. Synthetic biology has promising outlooks for biotechnology, and particularly for understanding the self-organizing principle of biological molecules and systems in life. He focuses on RNA and RNA protein (RNP) architectures to regulate cellular functions in a customized manner. Thus, he aims to develop new technologies and understand the design principles of biological molecules and systems by employing “bottom-up” synthetic approaches.

Latest News

• Aug. 20, 2014

  Hirohide Saito published ''Engineering RNA-protein complexes with different shapes for imaging and therapeutic applications'' in ACS Nano

• Sep. 18, 2013

  Hirohide Saito published "A versatile cis-acting inverter module for synthetic translational switches" in Nature Communications

• Sep. 18, 2013

  Hirohide Saito published "Quantitative and simultaneous translational control of distinct mammalian mRNAs"

• Sep. 18, 2013

  Hirohide Saito published "Directed evolution of a synthetic RNA–protein module to create a new translational switch"

• Dec. 3, 2012

  "Three-dimensionally designed protein-responsive RNA devices for cell signaling regulation" published in Nucleic Acids Research.

• Dec. 29, 2011

  "Feedback Control of Protein Expression in Mammalian Cells by Tunable Synthetic Translational Inhibition" (ACS Synthetic Biology)

• Jan. 19, 2011

  Synthetic human cell fate regulation by protein-driven RNA switches

• Jan. 17, 2011

  Synthetic RNA--protein complex shaped like an equilateral triangle.