The Hakubi Project

9th

The following 13 researchers are working at the Hakubi Center for Advanced Research, Kyoto University.

:Global Type
:Tenure-track Type

Short Introduction

All organisms are exposed to a wide variety of cellular stresses. It is therefore essential for organisms to sense stresses and induce defense programs. My research interests are focused on understanding how the body senses and responds to cellular stresses, including oxidative, hypoxic, and acidic stress. In the Hakubi-project, I plan to identify the acid-inducible transcription factor that normalizes intracellular pH levels. In general, tumor cells are exposed to low pH, compared with normal cells, due to enhanced glycolysis; therefore, the identification of acid-inducible transcription factor would lead to the elucidation of the mechanism how tumor cells are able to adapt to low pH conditions. The mechanisms underlying stress sensing are based on chemical reaction. I believe that my background in chemistry and chemical biology uniquely enables me to view cancer biology from a different perspective and bring a new area of expertise to the field.

Introduction Research(PDF)

Research activity status (external page)

Latest News

• Sep. 5, 2022

  Associate Professor Nobuaki Takahashi (Graduate School of Engineering) give a talk at National Museum of Nature and Science

• Nov. 10, 2020

  Associate Professor Nobuaki TAKAHASHI (Graduate School of Engineering) published a paper online. (Molecular Cell)

• Apr. 8, 2020

  Associate Professor Nobuaki TAKAHASHI (Graduate School of Engineering) received “The Young Scientists’ Prize, the Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology”.

• May. 29, 2019

  Hakubi Seminar Announcement (167th meeting)