No.36 Seminar : Adult Neurogenesis and Plasticity of the Brain
- Itaru IMAYOSHI(The Hakubi Center)
- 2012/03/06 4:00pm
- The Hakubi Center (iCeMS West Wing 2F, Seminar Room)
- English
Summary
Although mammalian neurogenesis is mostly completed by the perinatal period, new neurons are continuously generated in the subventricular zone of the lateral ventricle and the subgranular zone of the hippocampal dentate gyrus. Since the discovery of adult neurogenesis, many extensive studies have been performed on various aspects of adult neurogenesis, including proliferation and fate-specification of adult neural stem cells, and the migration, maturation and synaptic integration of newly born neurons. Furthermore, recent research has shed light on the intensive contribution of adult neurogenesis to olfactory-related and hippocampus-mediated brain functions. In this seminar, we discuss the recent findings about the integration mode of new neurons into the existing neural circuits. We further address the potential significance of adult neurogenesis in plasticity of the mammalian brain.