No.282 Seminar ： From the discovery of a novel inflammatory dendritic cell subset to its role in disease
- Daiya Ohara Assistant Professor, 15th batch, Institute for Life and Medical Sciences (LiME)
- 2026/03/03 4:45pm
- Research Administration Building, Basement Floor (Conference Rooms 1&2)
- Talk in Japanese, with slides in English
- Onsite and Zoom
Summary
Dendritic cells serve as the command center of the immune system and play an essential role in initiating immune responses. In recent years, increasing attention has been given to the diversity of dendritic cells, and it is now understood that the type of downstream T cell immune response is determined by which dendritic cell subsets are induced and activated.
T cell immune responses can be classified into three major types: type 1 immunity against viruses and intracellular bacteria, type 2 immunity against parasites, and type 17 immunity against fungi and extracellular bacteria. However, the dendritic cell subsets responsible for initiating each of these immune responses remain incompletely understood.
We recently identified a dendritic cell subset that initiates type 17 immune responses and uncovered its association with specific diseases. In this Hakubi Seminar, I will present our findings and discuss their implications for immune regulation and disease pathogenesis.