No.223 Seminar : Constructive understanding of phenotypic diversification in evolution of multicellular organisms
  • Associate Professor Toshiya ANDO (Hakubi 12th batch, Graduate School of Agriculture)
  • 2022/09/06 4:30pm
  • Zoom and onsite at the Hakubi Center for Advanced Research
  • English (Questions in Japanese are also acceptable.)
  • Zoom and onsite at the Hakubi Center for Advanced Research (Research Administration Building B1F)

Summary

Organisms have acquired novel phenotypes by accumulating various mutations in the genome during evolution and advanced into diverse environments. Recent advances in genome science have identified the key genetic loci involved in the phenotypic evolution in several organisms, many of which have accumulated complex mutations including large-scale chromosomal reorganization. It remains unclear which of these complex mutations drove phenotypic diversification and how. To address this issue, I have been recently developing chromosome manipulation techniques that can reconstitute “the large-scale complex mutations that occurred at the key genetic locus” that many multicellular organisms experienced in the past during phenotypic evolution. I will introduce my “reconstitutive evolutionary biology” approach to understand how chromosomal reorganization determine the direction of phenotypic evolution in the multicellular organisms, especially focusing on the ladybug wing color pattern evolution.

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Toshiya ANDO