No.110 Seminar ： Deciphering the “Ubiquitin codes”
- Minsoo Kim (The Hakubi Center for Advanced Research)
- 2016/03/15 4:30pm
- The Hakubi Center for Advanced Research (Research Administration Building 1F)
- English (this seminar is open for students and researchers at Kyoto Univ.)
Summary
Our body consists of functional molecules called “Proteins”. Proteins are made from the information on our DNA or genes, and are necessary to maintain a healthy body. After protein synthesis, their functions are modulated by several different type of modification.
I have been studying a small protein called “ubiquitin”, which is covalently attached to a target protein by a process called “ubiquitination”. This ubiquitination regulates the functions and degradation of target protein. Over the past 40 years, it has been thought that the ubiquitin system is limited only to eukaryotes. However, recent discoveries show that bacteria also use the same ubiquitination system to regulate protein functions. In this seminar, I would like to introduce the physiological significance of the “Ubiquitin Codes” during cell maintenance and disease development.