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Hiromi was born in Kawasaki, Kanagawa Prefecture. When he was an undergraduate student at Department of Agricultural Chemistry of University of Tokyo, where he expected to study organic chemistry, he was fascinated by a world of proteins that play a huge variety of delicate roles in biological systems. At first, he investigated how proteins work at atomic and molecular levels using X-ray crystallography and single-molecule detection techniques. His recent interest is to utilize function and nature of proteins to obtain information inside living cells and organisms. He is developing protein-based biosensors for visualization of energy metabolites at high spatial and temporal resolutions, which will facilitate understanding the mechanisms of how biological systems adapt their energy metabolic state in response to the environmental changes.